Vitamin B12 Mecobalamin Powder CAS 13422-55-4

Quality standard: EP/USP/CP/Company Standard Package: 1000g /tin; 500g / tin; 100g / tin; VB12 annual output: 24,000 KGS(pure)

Identification
Product name: Mecobalamin
Synonyms: Vitamin B12; Methyl-5,6-dimethylbenzimidazolylcobalamin
CAS Registry Number: 13422-55-4
Molecular Formula: C63H91CoN13O14P
Molecular Weight: 1344.38
EINECS: 236-535-3

Molecular Structure:

Physicochemical property
Mecobalamin is dark red crystals or crystalline powder; Slightly soluble in water ,and practically insoluble in acetonitrile; Affected by light.

Mecobalamin description
Mecobalamin is endogenous vitamin B12, which is present in blood and myeloid. Compared with vitamin B12, it has a good effect on the conduction of neurons. It can promote nucleic acid-protein through methylation reaction. Fat metabolism, as a coenzyme of methionine synthetase, can convert homocysteine to methionine, participate in the process of synthesis of thymidine by deoxynucleoside, promote nucleic acid, protein synthesis, promote intraaxial axonal transport and axis Regeneration and myelination, preventing axonal degeneration and repairing damaged nerve tissue. The peak plasma concentration was reached 3 hours after oral administration, and its absorption was dose dependent. The product can be detected from blood, kidney, adrenal gland, pancreas, liver and stomach tissue in turn, and the concentration is higher, while the concentration of muscle, testis, cranial nerve and the like is lower. Eight hours after taking, the total amount of B12 excreted in the urine was 40% to 80% of the excretion 24 hours after administration.

Application
Mecobalamin is used to treat megaloblastic anemia caused by vitamin B12 deficiency and also for peripheral neuropathy.